Synthetic and Medicinal Chemistry
Zasya has an expertise in synthetic and medical chemistry driven by the goal of helping customer accelerate the program to clinic. Providing chemistry support that covers all the stages of discovery from exploratory, hit to lead, lead optimization, to candidate selection.
We deliver expert solution to your complex problems in synthesis with a track record of delivering 15 preclinical candidates.
To accelerate your innovation, we combine scientific expertise and leading edge technology to deliver in desired molecules to customers.
Our synthetic and medicinal chemistry capabilities include
- Route design
- Custom synthesis
- Parallel synthesis
- Library design and synthesis
- Complex chemistries including pthalocyanines, polysaccharides and any challenging reactions
Chemical process R&D
Our chemical development team comprised of 20 scientists exceeds expectation on even challenging projects. We work closely with our customers to efficiently conduct route scouting and rapid fit for purpose development/optimization of reaction conditions for scale-up of materials for preclinical trials or large scale manufacturing under both non-GMP & GMP conditions. With support from our expert team of analytical chemists, chemical engineers & QA professionals we rapidly and efficiently develop scalable & manufacturing processes to meet any need.
Scale up capabilities
Coupled with the synthesis of process intermediates and GMP raw materials, we also offer c-GMP manufacturing of your API. Zasya handles small scale API critical for discovery & development under non-GMP conditions.
We can handle your non-GMP/GMP manufacturing needs seamlessly from grams to metric tons with out need for technology transfer to other company. Whether you require the material for toxicological studies, phase I-III clinical trials or commercial supplies. We leverage the expertise and technology to make your project a success.
Zasya has the right infrastructure to perform rapid scale-up. Our kilo-scale laboratories are equipped for the preparation for non-GMP/GMP starting materials and other processes intermediates on scale, from hundreds of grams to 100 of kilograms.
Capabilities
- Multiple jacketed glass reactors 10L to 3KL
- Large-scale hydrogenation capabilities 80L & 1000L non-GMP/GMP
- Temperatures -78 °C – 220 °C
Custom synthesis
Regardless of scale or complexity, we have expertize, capacity and capabilities to rapidly meet your custom synthesis needs from mg quantities of metabolite to several kilograms of a scaffold. We tailor our services to suit your needs applying chemical approaches depending on the complexity of your molecule.
For the quickest turnaround including the synthesis of reference standards, impurities, metabolites & scaffolds, we offer a suit of capabilities.
Additional chemical process R&D capabilities
- Preparation of APIs for non clinical safety studies
- Optimization of reaction conditions
- de-novo route design
Manufacturing
- Custom API manufacturing
- API & Intermediates catalogue
- Fine chemicals catalog
Custom API manufacturing
Zasya provides scientific expertise and state of the art technologies to support chemical development & c-GMP manufacture of complex APIs, including generics & potent compounds. Our facilities offer scale up/manufacturing at a cost effective price. Access of our portfolio of XX (link) commercial APIs, including generics along with our products & services in India.
Custom synthesis & contract manufacturing
We provide custom synthesis and contract manufacturing services at small & large-scale for all phases of discovery, development & manufacturing. Our teams brings extensive chemical & technical expertize to develop flexible, scalable solutions and cost effective processes tailored to your needs.
Our capabilities to your needs
- Cryogenic reactions
- Chiral synthesis
- Hazardous reactions
- Steroids
- Active pharmaceutical ingredients & intermediates catalog
- Fine chemicals catalog